All Products
ALL PRODUCTS
InSilicoTrials' Products
Hyper-accelerate drug and medical device development
Accelerate the development
of new drugs and medical devices
Significantly cut Research
and Development costs
Improve safety of
new drugs and medical devices
Products for Pharma
DISCOVERY
Drug Repurposing
DISCOVERY
Molecular Docking
Explores the interactions between a ligand towards a biological target at the molecular level, evaluates potential target-ligand combinations and quantifies target-ligand binding affinities
DISCOVERY
Epitopes Identification
Deep Learning-based. Predicts protein-protein interactions probability through 2D maps
DISCOVERY
Blood Brain Barrier Penetration
Machine Learning -based. Predicts Blood Brain Barrier penetration.
NONCLINICAL
Macrophages Polarization
Predicts phenotype changes towards M1 and M2 phenotypes (M1 and M2 scores) in an in vitro polarization experiment with customizable experimental conditions
NONCLINICAL
Chemotoxicity
Evaluates a compound’s toxicological prolife by in silico assessment of the major toxicological endpoints (e.g. genotoxicity, neurotoxicity, carcinogenicity, skin irritation, etc.)
NONCLINICAL
Mutagenicity
Assesses a compound’s mutagenicity potential by combining two complementary quantitative structure-activity methodologies, as by ICH M7 guidelines
NONCLINICAL
InSilicoIMMUNO
Immunogenicity Risk Screen
Early immunogenecity risk screen emulates the CD4+ T-cells proliferation assay to determine the potential immunogenicity risk of new protein sequences.
NONCLINICAL
InSilicoCARDIO
QT/TdP Risk Screen
A machine learning-based tool to predict a compound’s proarrhythmic risk using electrophysiology and machine learning.
NONCLINICAL
InSilicoCARDIO
STrhiPS
Enables in silico safety trials on a population of human-induced pluripotential stem cells
NONCLINICAL
InSilicoCARDIO
CiPA InSilico
Estimates Estimation of the safety marker qNet based on up to 7 ion channels in vitro data at different concentrations, as by FDA recommendations.
NONCLINICAL
Hemochromatosis
Predictions of the iron distribution and elimination pathway in a virtual hemochromatosis mouse based on a system-biology model.
NONCLINICAL
InSilicoENDO
Insulin Injection
Estimates insulin injection, skin absorption and residual volume in an injection port device over time via Computational Fluid Dynamics.
CLINICAL
InSilicoONCO
PCa GnRH Agonists Simulator
Enables simulations of clinical trials on a virtual population of prostate cancer patients being treated with a gonadotropin GnRH agonist.
CLINICAL
InSilicoONCO
CTx NeutroSim
Performs In silico clinical trials to assess the neutropenic effects of a chemotherapeutic agent in a virtual population of cancer patients.
CLINICAL
InSilicoNEURO
MS TreatSim
Generates in silico trials and personalized therapeutic effect predictions in relapsing-remitting multiple sclerosis, by predicting disease activity and treatment effects in virtual patients.
CLINICAL
InSilicoNEURO
Amyotrophic Lateral Sclerosis
Generates synthetic control arms for amyotrophic lateral sclerosis (ALS) clinical trials by predicting disease progression with virtual patients.
CLINICAL
InSilicoENDO
Infertility Virtual Patients
Simulates the (dys)functional hormonal system guiding the menstrual cycle and treatment effects in female virtual patients in assisted reproduction clinical trials
CLINICAL
InSilicoENDO
Polycystic Ovary Syndrome
Simulates disease progression and treatment effects in polycystic ovary syndrome (PCOS) virtual patients.
CLINICAL
InSilicoDIABETES
Diabetes Virtual Populations
Predicts the effect of anti-diabetic drugs and therapies in a virtual population.
CLINICAL
InSilicoVACCINE
InSilicoVaccine Suite
Computational tools for every step in the design and development of a vaccine or combination therapy, e.g. designing the vector, optimizing dose and schedule of existing vaccine, identifying effective adjuvants, and evaluating efficacy of combination therapies.
CLINICAL
REUMATOLOGY
Intra-Articular Injection
Analyzes dissolution, diffusion and transfer of drug from intra-articular knee space to the plasma, based on physiologically-based pharmacokinetic modeling.
MANUFACTURING
CMC
SimTabletCoater
Virtually experiment tablet coating process for pharmaceutical applications, in order to establish the desired setup in terms of coater rotation speed, mass of tablets in the coater, amount and composition of the spray applied over time.
MANUFACTURING
CMC
XPS
XPS (eXtended Particle Simulation) is a highly efficient simulation solution to better understand, control and predict pharmaceutical fluid-granular processes, to enhance efficiency and improve product quality.
Products for Medtech
NONCLINICAL
InSilicoCARDIO
Standard Testing for Balloon Expandable Devices
A suite comprehensive of various in silico reproductions of standard tests to assess the performance of balloon-expandable stents or heart valve substitutes.
NONCLINICAL
InSilicoCARDIO
SEV Radial Force Test
In silico reproduction of Radial Force test in self-expandible heart valve prostheses, following ISO 5840-3 standard.
NONCLINICAL
InSilicoCARDIO
Aorta Fluid Dynamics Tool
Tool based on a deep learning framework and computational fluid dynamics model to evaluate the flow dynamics in the thoracic aorta.
CLINICAL
InSilicoCARDIO
Left Atrial Appendage Occluder (LAAO) Implant in Patient-Specific Anatomies
Computational fluid dynamics simulation of LAAO to improve patient selection, optimize device settings to minimize the risk of device-related thrombus and predict treatment response.
NONCLINICAL/ CLINICAL
InSilicoCARDIO
Thoracic EndoVascular Aortic Repair (TEVAR)
Computational fluid dynamics simulation of stent-graft deployment to support device optimization and preoperative planning by studying pre- and post-TEVAR hemodynamics.
CLINICAL
InSilicoCARDIO
Cardiac Arrythmia
Electrophysiological models of the heart to support prevention, diagnosis and treatment of cardiac diseases.
NONCLINICAL/ CLINICAL
InSilicoCARDIO
Catheter Lead Navigation and Ablation
Electrical and mechanical simulation of lead navigation and ablation to support device optimization and procedure planning.
NONCLINICAL
InSilicoCARDIO
Pulmonary Vein Isolation
Structural simulations to support the evaluation of procedure safety in terms of mechanical stresses, perforation risk and tissue temperature increase.
CLINICAL
InSilicoCARDIO
Flow Diverter Implantation in Cerebral Aneurysms
Structural and Computational fluid dynamics simulation of flow diverter deployment and performance in patient-specific anatomies of intracranial aneurysmatic vessel.
NONCLINICAL
InSilicoCARDIO
Anti-Inflammatory
Drug-Eluting Pacing Leads
Drug release simulations to optimize the design of new drug-eluting collars mounted on pacing leads.
NONCLINICAL
InSilicoORTHO
In Silico Standard Testing of Hip Femoral Stems
Evaluation of static implant stresses and strains of device designs for non-modular metallic hip femoral stems, following the ASTM F2996-20 standard.
NONCLINICAL
InSilicoORTHO
In Silico Standard Testing of Total Knee Femoral Components
Evaluation of static implant stresses and strains of device designs for metallic total knee femoral components, following the ASTM F3161-16 standard.
NONCLINICAL
InSilicoORTHO
In Silico Standard Testing of Total Knee Tibial Components
Evaluation of static implant stresses and strains of device designs for Metallic Total Knee Tibial Components.
CLINICAL
InSilicoORTHO
Virtual CranioMaxilloFacial Surgery
Patient-specific design assisted by simulations to predict the outcome of the intervention.
CLINICAL
InSilicoNEPHRO
End Stage Kidney Failure
Automated prediction and histologic scoring kidney failure in IgA nephropathy, also known as Berger’s disease nephropathy, based on artificial intelligence.
CLINICAL
InSilicoNEPHRO
Kidney Biopsy Classification
Automated clinical classification of kidney biopsy from direct immunofluorescence, based on artificial intelligence.
CLINICAL
InSilicoNEPHRO
ADPKD Segmentator
Fast and accurate estimation of Autosomal Dominant Polycystic Kidney Disease risk classification and progression, based on automated kidney and cysts segmentation from MRI data.
NONCLINICAL
InSilico3DPRINT
InSilico3DPRINT
Digital workflow to virtually assess safety and performance of 3D-printed custom medical devices before prototyping and manufacturing.
NONCLINICAL
InSilicoMRI
NuMRis
Assessment of radiofrequency-induced heating on or near passive implants during magnetic resonance imaging, following the ASTM F2182-19e2 standard
NONCLINICAL
InSilicoRESPIRATORY
Drug Inhaler Combination
Computational fluid dynamics simulations to optimize the design of a spray device for drug administration.
NuMRis
Assessment of radiofrequency-induced heating of passive devices following the ASTM F2182-19e2 standard.
NuMRis
Assessment of radiofrequency-induced heating of passive devices following the ASTM F2182-19e2 standard.