InSilicoTrials is the first cloud-based platform that provides healthcare companies and researchers with easy-to-use tools to perform computational modeling and simulation in pharmaceutical and medical devices development

How it works

The platform offers users two computational options:

  • to select the model of choice from the digital library
  • to develop or to upload their own model

The platform enables users to input parameters of choice into the model. For a model from the digital library, parameters choices are guided by best practice ranges.
Simulations are launched and run on protected and secured Microsoft Azure Cloud computing resources.
Completion of the modeling and simulation is notified to the users via e-mail.
The platform enables users to view and analyze the modeling and simulation results and to optimize modeling and simulation scenario’s depending on objectives.


InSilicoMRI is a module for the investigation of the radiofrequency (RF)-induced heating of passive devices in a 3T MRI scanner.

One of the possible risks posed to a patient with implanted devices during MRI is that conductive structures may pick up RF-energy during the exposure, and locally deposit it as heating in tissue near the implant. To assess the compatibility level, the manufacturer of the medical device has to perform tests to predict the hazard in the worst-case exposure scenario. InSilicoMRI is designed to study the MRI compatibility, for different exposure conditions, of implantable devices (e.g. stents) with different dimensions, configurations or designs.

InSilicoMRI has been implemented in collaboration with the FDA and ANSYS to support the broadening use of computer modeling and simulation for electromagnetic safety analysis prior to a medical device submission. The models used within the simulation (stent, phantom, and RF coil) were provided by the Center for Devices and Radiological Health within the U.S. Food and Drug Administration (FDA-CDRH). The simulation steps are designed to replicate the ASTM F2182-11a Standard.

Why should I use it?

Develop and run your model

Easy access to models in Digital Library

Guaranteed data protection and cybersecurity

On-demand cloud computing

Ready-to-use computational environment

Option to report as by regulatory guidelines


InSilicoTrials enables you to run the model of your choice with widely adopted software in a pre-configured and integrated framework, and you pay what you use. Engineers, designers, researchers, clinicians use our technological solutions for product design, development, testing and decision making.

ANSYS, the global leader in engineering simulation, provides engineering simulation software to help customers solve the most complex design challenges and engineer successful, innovative products faster and at lower cost.


InSilicoTrials allows you to run your simulations on scalable and on-demand computing resources, tailored on your modeling needs.
The cloud-based computational hub is conform to global standards and grants data protection and cybersecurity.

Azure offers a platform to develop solutions for in silico medicine and personalized healthcare, providing on-demand compute resources that enable to run large parallel and batch compute jobs in the cloud.