Drug Safety Suite2

DRUG SAFETY SUITE

Drug-induced
cardiac toxicity

Complement in vitro testing to assess drug-induced proarrhythmic risks in drug candidates early screening.

Neurology

Oncology

Nefrology

500+

Days faster than traditional approach

25%

Cheaper than usual

The Pursuit of Excellence in New Drug Development

A huge decrease of
R&D costs and time

The ICHS7B and ICH E14 guidelines will be soon replaced by one that will regulate both preclinical and clinical studies. The comprehensive In Vitro proarrhythmya Assay (CiPA) initiative has the goal of increasing cardiac safety and it recommends testing on 7 ionic channels instead of one and the complementary use of in silico tools to simulate the impact of a drug candidate on the ventricular Action Potential of human cardiomyocyte cells.

Identify the drug candidate safety window

In silico testing helps also to identify the drug candidate safety window, through virtual screening of multiple concentrations, guiding in vitro and in vivo testing and resulting in a drastic reduction of risks and investments.

Discover our Drug Safety Suite of online products

QT/TdP Risk Screen

A unique tool to calculate safety markers and estimate clinical risks following CredibleMeds classification for multiple concentrations of a compound against the four most relevant ion currents, and in minutes.

STrhiPS

A tool to conduct in silico safety trials on a population of human-induced pluripotential stem cells, for up to 7 ion currents and at different concentrations.

CiPA In Silico

A tool based on the FDA standards, to calculate the safety marker qNet on up to 7 ion currents at different concentrations.

Start simulating now